C15orf23 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-40192-20uL | 20uL | £120.00 |
Quantity:
E-AB-40192-60uL | 60uL | £160.00 |
Quantity:
E-AB-40192-120uL | 120uL | £230.00 |
Quantity:
E-AB-40192-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
C15orf23
Background:
Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Calculated MW:
35 kDa
Concentration:
2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant Human Small kinetochore-associated protein protein
ObservedMW:
35 kDa
Purification method:
Affinity purification
Target Synonym:
KNSTRN;C15orf23;chromosome 15 open reading frame 23;HSD11;Kinastrin;Kinetochore-localized astrin-binding protein;Kinetochore-localized astrin/SPAG5-binding protein;Putative TRAF4-associated factor 1;SKAP;small kinetochore associated protein;T4AF1;TRAF4 associated factor 1;TRAF4-associated factor 1;Traf4af1
UNIProt ID:
Q9Y448