BCL6 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-61563-60uL | 60uL | £210.00 |
Quantity:
| E-AB-61563-120uL | 120uL | £291.00 |
Quantity:
| E-AB-61563-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
BCL6
Background:
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
72kDa/78kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human BCL6 (NP_001697.2).
ObservedMW:
110kDa
Purification method:
Affinity purification
Target Synonym:
BCL6;BCL5;BCL6A;LAZ3;ZBTB27;ZNF51
UNIProt ID:
P41182
References
- https://link.springer.com/article/10.1007/s00005-020-00596-0