AREG Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-64299-60uL | 60uL | £210.00 |
Quantity:
| E-AB-64299-120uL | 120uL | £291.00 |
Quantity:
| E-AB-64299-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
AREG
Background:
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
27kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000 IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human AREG (NP_001648.1).
ObservedMW:
44kDa
Purification method:
Affinity purification
Target Synonym:
AREG;AR;AREGB;CRDGF;SDGF;amphiregulin
UNIProt ID:
P15514