AR Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70112-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70112-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70112-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
AR
Background:
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
0.83 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:300-1:1000
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Androgen receptor
Purification method:
Affinity purification
Target Synonym:
AIS;ANDR;Androgen nuclear receptor variant 2;Androgen receptor (dihydrotestosterone receptor;testicular feminization;spinal and bulbar muscular atrophy;Kennedy disease);Androgen receptor;androgen receptor splice variant 4b;AR;AR8;DHTR;Dihydro testosterone receptor;Dihydrotestosterone receptor (DHTR);Dihydrotestosterone receptor;HUMARA;HYSP1;KD;Kennedy disease (KD);NR3C4;Nuclear receptor subfamily 3 group C member 4 (NR3C4);Nuclear receptor subfamily 3 group C member 4;SBMA;SMAX1;Spinal and bulbar muscular atrophy (SBMA);Spinal and bulbar muscular atrophy;Testicular Feminization (TFM);TFM
UNIProt ID:
P10275;P19091;P15207