FITC Anti-Mouse CD161/NK1.1 Antibody[PK136]

Elabscience
Product Code: E-AB-F0987C
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-F0987C-50Tests50Tests£95.00
Quantity:
E-AB-F0987C-100Tests100Tests£109.00
Quantity:
E-AB-F0987C-100Testsx2100Testsx2£125.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2a, κ
Antibody Clone: PK136
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Images

1 / 1
C57BL/6 murine splenocytes are stained with FITC Anti-Mouse CD161/NK1.1 Antibody and APC Anti-Mouse CD49b Antibody (Left). Unstained splenocytes are used as control.

C57BL/6 murine splenocytes are stained with FITC Anti-Mouse CD161/NK1.1 Antibody and APC Anti-Mouse CD49b Antibody (Left). Unstained splenocytes are used as control.

Documents

Further Information

Abbreviation:
CD161/NK1.1
Background:
NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
FITC
GeneID:
17059
Target Synonym:
Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;CD161 antigen-like family member C;Ly-55c;CD161/NK1.1;NKR-P1.9;NKR-P1C;NKR-P1 40;CD161c;
UNIProt ID:
P27814;P27812;Q99JB4;
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

References

  • https://www.sciencedirect.com/science/article/pii/S1383571821000280

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