Biotin Anti-Mouse CD8a Antibody[53-6.7]

Elabscience
Product Code: E-AB-F1104B
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-F1104B-25ug25ug£93.00
Quantity:
E-AB-F1104B-100ug100ug£122.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rat
Antibody Isotype: Rat IgG2a, κ
Antibody Clone: 53-6.7
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C. Do not freeze.

Documents

Further Information

Abbreviation:
CD8a
Background:
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
0.5 mg/mL
Conjugation:
Biotin
GeneID:
12525
Target Synonym:
T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
UNIProt ID:
P01731
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is < 1.0 ug per 10^6 cells in 100 uL volume or 100 uL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

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