Biotin Anti-Human CD4 Antibody[RPA-T4]

CD4

CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

0.5 mg/mL

Biotin

920

T-cell surface glycoprotein CD4;CD4;T-cell surface antigen T4/Leu-3;CD4;

P01730

Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is < 1.0 ug per 10^6 cells in 100 uL volume or 100 uL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.