ANP32A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-61107-60uL | 60uL | £210.00 |
Quantity:
| E-AB-61107-120uL | 120uL | £291.00 |
Quantity:
| E-AB-61107-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ANP32A
Background:
Multifunctional protein that is involved in the regulation of many processes including tumor suppression, apoptosis, cell cycle progression or transcription. Promotes apoptosis by favouring the activation of caspase-9/CASP9 and allowing apoptosome formation. In addition, plays a role in the modulation of histone acetylation and transcription as part of the INHAT (inhibitor of histone acetyltransferases complex. Inhibits the histone-acetyltranferase activity of EP300/CREBBP (CREB-binding protein and EP300/CREBBP-associated factor by histone masking. Preferentially binds to unmodified histone H3 and sterically inhibiting its acetylation and phosphorylation leading to cell growth inhibition. Participates in other biochemical processes such as regulation of mRNA nuclear-to-cytoplasmic translocation and stability by its association with ELAVL1 (Hu-antigen R. Plays a role in E4F1-mediated transcriptional repression as well as inhibition of protein phosphatase 2A.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
28kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human ANP32A
ObservedMW:
28kDa
Purification method:
Affinity purification
Target Synonym:
ANP32A;C15orf1;HPPCn;I1PP2A;LANP;MAPM;PHAP1;PHAPI;PP32
UNIProt ID:
P39687