AIF1 Polyclonal Antibody

Elabscience
Product Code: E-AB-70324
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-70324-60uL60uL£184.00
Quantity:
E-AB-70324-120uL120uL£251.00
Quantity:
E-AB-70324-200uL200uL£351.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry analysis of paraffin-embedded mouse brain  using AIF1 Polyclonal Antibody at dilution of 1:300.
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Immunohistochemistry analysis of paraffin-embedded Rat brain  using AIF1 Polyclonal Antibody at dilution of 1:300.

Immunohistochemistry analysis of paraffin-embedded mouse brain  using AIF1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Rat brain  using AIF1 Polyclonal Antibody at dilution of 1:300.

Documents

Further Information

Abbreviation:
AIF1
Background:
This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
1.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:200-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to HumanIBA-1
Purification method:
Affinity purification
Target Synonym:
AIF 1;AIF-1;Aif1;AIF1 protein;AIF1;Allograft inflammatory factor 1;Allograft inflammatory factor 1 splice variant G;allograft inflammatory factor-1 splice variant Hara-1;balloon angioplasty responsive transcription;BART 1;G1;G1 putative splice variant of allograft inflamatory factor 1;IBA 1;IBA1;interferon gamma responsive transcript;Interferon responsive transcript 1;interferon responsive transcript factor 1;Ionized calcium binding adapter molecule 1;Ionized calcium-binding adapter molecule 1;ionized calcium-binding adapter molecule;IRT 1;IRT1;Microglia response factor;MRF1;Protein g1
UNIProt ID:
O70200,P55009

References

  • https://www.sciencedirect.com/science/article/pii/S0006899322001822
  • https://link.springer.com/article/10.1007/s12640-023-00637-4