ACVR2A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-60537-60uL | 60uL | £210.00 |
Quantity:
| E-AB-60537-120uL | 120uL | £291.00 |
Quantity:
| E-AB-60537-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ACVR2A
Background:
This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:200 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human ACVR2A (NP_001607.1).
Purification method:
Affinity purification
Target Synonym:
ACVR2A;ACTRII;ACVR2
UNIProt ID:
P27037
References
- https://onlinelibrary.wiley.com/doi/abs/10.1002/dta.2346