ACTN1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70225-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70225-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70225-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ACTN1
Background:
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
102-107kDa
Concentration:
0.66 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:3000
Immunogen:
Recombinant protein corresponding to Mouseα-actinin1
ObservedMW:
110kDa
Purification method:
Affinity purification
Target Synonym:
actinin 1 smooth muscle;Actinin alpha 1;actinin;alpha 1;ACTN 1;Actn1;ACTN1;Alpha Actinin 1;Alpha actinin cytoskeletal isoform;Alpha-actinin cytoskeletal isoform;Alpha-actinin-1;BDPLT15;F actin cross linking protein;F-actin cross-linking protein;FLJ40884;FLJ54432;Non muscle alpha actinin 1;Non-muscle alpha-actinin-1
UNIProt ID:
P12814,Q7TPR4,Q9Z1P2