Recombinant Mouse TGFB2 Protein (Active)
| Code | Size | Price |
|---|
| PKSM041168-10ug | 10ug | £219.00 |
Quantity:
| PKSM041168-50ug | 50ug | £497.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
TGFB2
Accession:
P27090
Activity:
Immobilized Mouse TGFB2 at 10ug/ml(100 ul/well) can bind Human TGFBR2-FC(Cat: PKSH033426). The ED50 of Mouse TGFB2 is 22ug/mL.
Background:
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
Calculated MW:
12.7 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 4 mM HCl.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
25-28 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala303-Ser414
Target Synonym:
TGFB2;BSC-1 cell growth inhibitor;Cetermin;Glioblastoma-derived T-cell suppressor factor;G-TSF;MGC116892;Polyergin;TGF-beta2;TGF-beta-2;transforming growth factor beta-2
UNIProt ID:
P27090