Recombinant Mouse TSLP Receptor/CRLF2 Protein (Fc Tag)
| Code | Size | Price |
|---|
| PKSM041158-10ug | 10ug | £219.00 |
Quantity:
| PKSM041158-50ug | 50ug | £497.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Shipping:
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
TSLP Receptor;CRLF2
Accession:
Q8CII9
Background:
The cytokine thymic stromal lymphopoietin receptor (TSLPR) is consisting of a common γ receptor?like chain (TSLPR-γ) and a common interleukin 7 (IL-7) Rα chain that belongs to the type 1 cytokine receptor family. Transfection of TSLPR cDNA result in only low affinity binding, while cotransfection of the IL-7Rα chain cDNA shows high affinity binding. TSLP and TSLPR play a critical role in the initiation of allergic diseases in mice. The TSLP R cDNA encodes a transmembrane receptor containing 370 amino acids (aa) with two potential N-linked glycosylation sites and a cytoplasmic domain of 104 aa including a single tyrosine residue. TSLPR can mediate signaling of the signal transducer and activator of transcription 5 (Stat5) by TSLP. TSLP R is broadly expressed in the immune and hematopoietic cells, particularly in hematopoietic progenitors and myeloid cells.
Calculated MW:
49.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
62-88 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala20-Leu233
Target Synonym:
CRL2;CRLF2;CRL2 cytokine receptor;cytokine receptor-like factor 2;ILXR;IL-XR;P2RY8/CRLF2 fusion;Thymic stromal lymphopoietin protein receptor;Thymic stromal-derived lymphopoietin receptor;TSLP receptor;TSLPR
UNIProt ID:
Q8CII9