Recombinant Mouse CD300a/LMIR1 Protein (Fc Tag)
| Code | Size | Price |
|---|
| PKSM041101-10ug | 10ug | £170.00 |
Quantity:
| PKSM041101-50ug | 50ug | £349.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Shipping:
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
CD300a;LMIR1
Accession:
Q6SJQ0
Background:
LMIR1, also termed CD300a, is a type I transmembrane glycoprotein with a single IgV-like extracellular domain and an extended membrane proximal region that links the immunoglobulin (Ig) and transmembrane domains and belongs to the immunoglobulin superfamily. The intracellular domain of LMIR1 contains several immunoreceptor tyrosine-based inhibition motifs (ITIMs). When cross-linked, it will be tyrosine phosphorylated and capable of recruiting tyrosine phosphatases (SHP-1, SHP-2) and inositol polyphosphate 5-phosphatase, SHIP. LMIR1 will regulate mast cell-mediated inflammatory responses. LMIR1 is broadly expressed on myeloid and lymphoid cells, and its expression is differentially regulated depending on the cell type.
Calculated MW:
44.3 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
58-75 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Leu28-Arg183
Target Synonym:
CD300a;CD300a antigen;CMRF35H9;CD300a molecule;leukocyte immunoglobulin-like receptor;CD300 antigen-like family member A;CMRF35-like molecule 8;NK inhibitory receptor;Immunoglobulin superfamily member 12;IRp60;Inhibitory receptor protein 60;CLM8;CMRF-35H;IGSF12;IRC1;IRC2;LMIR1;CLM-8;MAIR-I;Clm8;MAIR-I;MAIR-Ia;mcpir1;MMAC8;Pigr4
UNIProt ID:
Q6SJQ0