Recombinant Mouse Glypican-1/GPC1 Protein (His Tag)(Active)
| Code | Size | Price |
|---|
| PKSM041030-10ug | 10ug | £170.00 |
Quantity:
| PKSM041030-50ug | 50ug | £315.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
Glypican-1;GPC1
Accession:
Q9QZF2
Activity:
Immobilized Human FGFb(Cat: PKSH032437) at 2ug/ml(100 ul/well) can bind Mouse GPC1-His. The ED50 of Mouse GPC1-His is 786 ng/ml.
Background:
Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. It is required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.
Calculated MW:
56.7 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
56 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Asp24-Ser529
Target Synonym:
Glypican-1;Gpc1
UNIProt ID:
Q9QZF2