Recombinant Mouse Fibrillin-1/FBN1 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSM041018-10ug | 10ug | £219.00 |
Quantity:
| PKSM041018-50ug | 50ug | £497.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
Fibrillin-1;FBN1
Accession:
Q61554
Background:
Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. In the liver asprosin activates rapid glucose release by a cAMP-dependent pathway. The glucose release by the liver into the blood stream is vital for brain function and survival during fasting. People with neonatal progeroid syndrome lack asprosin, while people with insulin resistance have it in abundance. In animal tests asprosin showed potential for treating type 2 diabetes. When antibodies targeting asprosin were injected into diabetic mice, blood glucose and insulin levels improved.
Calculated MW:
16.9 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-8His
ObservedMW:
30 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Ser2732-His2871
Target Synonym:
Fibrillin-1;Fbn1;Asprosin;Fbn-1
UNIProt ID:
Q61554
References
- https://www.tandfonline.com/doi/abs/10.1080/13813455.2021.1894178