Recombinant Mouse Ephrin-A5/EFNA5 Protein (His Tag)(Active)
| Code | Size | Price |
|---|
| PKSM041010-10ug | 10ug | £170.00 |
Quantity:
| PKSM041010-50ug | 50ug | £315.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
Ephrin-A5;EFNA5
Accession:
O08543
Activity:
Immobilized Human EphA8-Fc(Cat: PKSH032386) at 1. 5ug/ml(100 ul/well) can bind Human EFNA5-His. The ED50 of EFNA5-His is 12.63ug/ml.
Background:
Ephrin-A5 is a glycosylphosphatidylinositol (GPI)-anchored protein of the ephrin-A subclass of ephrin ligands that binds to the EphA subclass of Eph receptors. Ephrin-A5 has also been shown to bind to the EphB2 receptor. It is crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin-A5 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.
Calculated MW:
22.5 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
25-28 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Gln21-Gln206
Target Synonym:
Ephrin-A5;AL-1;EPH-related receptor tyrosine kinase ligand 7;Epl7;Eplg7;Lerk7;Efna5;
UNIProt ID:
O08543