Recombinant Mouse Carbonic Anhydrase 14/Car14 Protein (His Tag)(Active)
| Code | Size | Price |
|---|
| PKSM040972-10ug | 10ug | £256.00 |
Quantity:
| PKSM040972-50ug | 50ug | £553.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Shipping:
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Further Information
Abbreviation:
Carbonic Anhydrase 14;Car14
Accession:
Q9WVT6
Activity:
Measured by its esterase activity. The specific activity is 6556. 875 pmol/min/ug, as measured under the described conditions.
Background:
Mouse Ca14,also known as Carbonic anhydrase 14,is a member of large family of zinc metalloenzymes .It could catalyze reversible hydration of carbon dioxide. The reaction is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Fifteen CA isoforms have been reported so far. They have different patterns of tissue-specific expression and physiologic roles. Some CAs may serve as markers for tumors and hypoxia. CA XIV is a polypeptide consisting of an extracellular N-terminal catalytic domain, a membrane-spanning segment and a short intracellular C- terminal segment with several potential phosphorylation sites. A subset of CAs lack CA activity due to point mutations but retain esterase function. CA14 is widely expressed in the central nervous system
Calculated MW:
31.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris,150mM NaCl,pH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
41-50 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala16-Met290
Target Synonym:
Carbonic Anhydrase 14;Carbonate Dehydratase XIV;Carbonic Anhydrase XIV;CA-XIV;CA14;
UNIProt ID:
Q9WVT6