Recombinant Human Semaphorin 4D/SEMA4D Protein (Fc Tag)(Active)
| Code | Size | Price |
|---|
| PKSH033023-10ug | 10ug | £166.00 |
Quantity:
| PKSH033023-50ug | 50ug | £315.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Further Information
Abbreviation:
SEMA4D;CD100
Accession:
Q92854
Activity:
Immobilized Mouse PLXDC2 -His(Cat: PKSH032037) at 2ug/ml(100 ul/well) can bind Human SEMA4D-Fc.
Background:
Semaphorin-4D is also known as A8;BB18; GR3; CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain; 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells; regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2; which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.
Calculated MW:
106.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
130-170 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met22-Arg734
Target Synonym:
Semaphorin-4D;A8;BB18;GR3;CD100;C9orf164;CD100;coll-4;M-sema-G;SEMAJ
UNIProt ID:
Q92854