Recombinant Human RANK/TNFRSF11A Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH032987-10ug | 10ug | £166.00 |
Quantity:
| PKSH032987-50ug | 50ug | £315.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Further Information
Abbreviation:
RANK;TNFRSF11A
Accession:
Q9Y6Q6
Background:
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.
Calculated MW:
21.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
25-30 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ile30-Pro212
Target Synonym:
CD265;ODFR;TNFRSF11A;TRANCE R;CD265;CD265 antigen;FEO;ODFROSTS;OFE;OPTB7;PDB2;RANK1;Receptor activator of NF-KB;receptor activator of nuclear factor-kappa B;TRANCER;tumor necrosis factor receptor superfamily member 11A
UNIProt ID:
Q9Y6Q6