Recombinant Human PTPN6/SH-PTP1 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH032975-10ug | 10ug | £256.00 |
Quantity:
| PKSH032975-50ug | 50ug | £553.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage:
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Further Information
Abbreviation:
PTPN6;SH-PTP1
Accession:
P29350-2
Background:
Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. In addition, PTP1C also modulates signaling by tyrosine phosphorylated cell surface receptors.
Calculated MW:
35.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Supplied as a 0.2 um filtered solution of 25mM Tris-HCl, 2mM β-ME, 1mM EDTA, 1mM DTT, 20% Glycerol, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
33 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Lys243-Ile541
Target Synonym:
Tyrosine-Protein Phosphatase Non-Receptor Type 6;Hematopoietic Cell Protein-Tyrosine Phosphatase;Protein-Tyrosine Phosphatase 1C;PTP-1C;Protein-Tyrosine Phosphatase SHP-1;SH-PTP1;PTPN6;HCP;PTP1C
UNIProt ID:
P29350