Recombinant Human PSA/KLK3 Protein (aa 25-261, His Tag)

Elabscience
Product Code: PKSH032949
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PKSH032949-10ug10ug£256.00
Quantity:
PKSH032949-50ug50ug£553.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Shipping:
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months

Documents

Further Information

Abbreviation:
PSA;KLK3
Accession:
P07288
Background:
KLK3; also known as APS; is short for Prostate-specific antigen. It is a 261 aa. protein which belongs to the peptidase S1 family and Kallikrein subfamily. This protein has 5 isforms produced by alternative splicing. It is a secreted protein and can forms a heterodimer with SERPINA5 which can inhibit its activity. KLK3 is also strongly inhibited by Zn2+; 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins; which are avid zinc binders. KLK3 can hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Calculated MW:
27.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl;1mM CaCl2;pH7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
35 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ile25-Pro261
Target Synonym:
APS;Hk3;KLK2A1;PSA;Prostate-Specific Antigen;PSA;Gamma-Seminoprotein;Seminin;Kallikrein-3;P-30 Antigen;Semenogelase;
UNIProt ID:
P07288