Recombinant Human POMGNT1 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH032917-10ug | 10ug | £256.00 |
Quantity:
| PKSH032917-50ug | 50ug | £553.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Further Information
Abbreviation:
POMGNT1
Accession:
Q8WZA1
Background:
Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3).
Calculated MW:
69.3 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
74 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Leu59-Thr660
Target Synonym:
Protein O-Linked-Mannose Beta-1;2-N-Acetylglucosaminyltransferase 1;POMGnT1;UDP-GlcNAc:Alpha-D-Mannoside Beta-1;2-N-Acetylglucosaminyltransferase I.2;POMGNT1;MGAT1.2
UNIProt ID:
Q8WZA1