Recombinant Human NCR3/NKp30 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH032786-10ug | 10ug | £192.00 |
Quantity:
| PKSH032786-50ug | 50ug | £411.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Further Information
Abbreviation:
NCR3;NKp30
Accession:
O14931
Background:
Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed ?Natural Cytotoxicity Receptors?. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition; NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signaling specifically induces lytic activity against several tumor cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity.
Calculated MW:
12.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
26 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Leu19-Thr138
Target Synonym:
Natural Cytotoxicity Triggering Receptor 3;Activating Natural Killer Receptor p30;Natural Killer Cell p30-Related Protein;NK-p30;NKp30;CD337;NCR3;1C7;LY117;DAAP-90L16.3;MALS
UNIProt ID:
O14931