Recombinant Human/Mouse/Rat/Rhesus/Canine BMP-2 Protein (Active)
| Code | Size | Price |
|---|
| PKSH031986-20ug | 20ug | £444.00 |
Quantity:
| PKSH031986-100ug | 100ug | £825.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Cell Culture
Shipping:
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Further Information
Abbreviation:
BMP-2
Accession:
NP_001191.1
Activity:
Measured by its ability to induce alkaline phosphatase production by MC3T3-E1 mouse osteoblastic cells. The ED50 for this effect is typically 0.5-2 ug/ml.
Background:
BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
Calculated MW:
13 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile 30 % CAN, 0.1 % TFA, pH 2.9.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gln283-Arg396
Target Synonym:
BDA2;BDA2A;BMP-2;BMP2A;BMP2