Recombinant Human LAMP2/CD107b Protein (His Tag)(Active)
| Code | Size | Price |
|---|
| PKSH032684-10ug | 10ug | £155.00 |
Quantity:
| PKSH032684-50ug | 50ug | £287.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Further Information
Abbreviation:
LAMP2;CD107b
Accession:
P13473
Activity:
Immobilized Human LGALS3(Cat: PKSH032474) at 1. 5ug/ml(100 ul/well) can bind Human LAMP2-His. The ED50 of Human LAMP2-His is 12.73 ug/ml.
Background:
Lysosomal Associated Membrane Protein 2 (LAMP2) is a major component of lysosomal membranes. LAMP2 is a transmembrane glycoprotein about 110kDa. Mature human LAMP2 consists of a 347 amino acid (aa) intralumenal domain, a 24 aa transmembrane segment, and a 35 aa cytoplasmic tail . The lumenal domain is organized into two heavily N-glycosylated regions. Alternate splicing generates a human LAMP2 isoform (LAMP2B) with a substituted juxtamembrane lumenal region, cytoplasmic tail and transmenmbrane segment.LAMP2 itself can cleavage lysosomal luminal domain and degradation lysosomal. In the help of chaperone HSC73,LAMP2 mediates the lysosomal uptake in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles.
Calculated MW:
33.9 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
78 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Leu29-Ile375
Target Synonym:
Lysosome-Associated Membrane Glycoprotein 2;LAMP-2;Lysosome-Associated Membrane Protein 2;CD107 Antigen-Like Family Member B;CD107b;LAMP2
UNIProt ID:
P13473