Recombinant Human LAMP1/CD107a Protein (Fc Tag)(Active)
| Code | Size | Price |
|---|
| PKSH032683-10ug | 10ug | £170.00 |
Quantity:
| PKSH032683-50ug | 50ug | £315.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Further Information
Abbreviation:
LAMP1;CD107a
Accession:
P11279
Activity:
Immobilized Human LGALS3(Cat#PKSH032474) at 2ug/ml (100 ul/well) can bind Human LAMP1-Fc. The ED50 of Human LAMP1-Fc is 1-5 ug/ml.
Background:
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes; endosomes; and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers; as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium; therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
Calculated MW:
65.5 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB;150mM NaCl;pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
106 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala29-Met382
Target Synonym:
Lysosome-Associated Membrane Glycoprotein 1;LAMP-1;Lysosome-Associated Membrane Protein 1;CD107 Antigen-Like Family Member A;CD107a;LAMP1;CD107a;LAMPA;LGP120
UNIProt ID:
P11279