Recombinant Human Kallikrein 1/KLK1 Protein (His Tag)

Elabscience
Product Code: PKSH032664
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PKSH032664-10ug10ug£256.00
Quantity:
PKSH032664-50ug50ug£553.00
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Overview

Host Type: Human
Regulatory Status: RUO
Shipping:
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months

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Further Information

Abbreviation:
Kallikrein 1;KLK1
Accession:
P06870
Background:
Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.
Calculated MW:
28.2 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl2, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
38 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Pro19-Ser262
Target Synonym:
Kallikrein-1;Kidney/Pancreas/Salivary Gland Kallikrein;Tissue Kallikrein;KLK1
UNIProt ID:
P06870