Recombinant Human IDH1 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH032659-10ug | 10ug | £256.00 |
Quantity:
| PKSH032659-50ug | 50ug | £553.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Further Information
Abbreviation:
IDH1
Accession:
O75874
Background:
Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer; binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions; such as the conversion of 2; 4-dienoyl-CoAs to 3-enoyl-CoAs; as well as in peroxisomal reactions that consume 2-oxoglutarate; namely the α-hydroxylation of phytanic acid.
Calculated MW:
48.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Supplied as a 0.2 um filtered solution of 50mM Tris, 200mM NaCl, 10% glycerol, pH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-8His
ObservedMW:
39-54 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Leu414
Target Synonym:
Isocitrate Dehydrogenase [NADP] Cytoplasmic;IDH;Cytosolic NADP-Isocitrate Dehydrogenase;IDP;NADP(+)-Specific ICDH;Oxalosuccinate Decarboxylase;IDH1;PICD
UNIProt ID:
O75874