Recombinant Human FGF-12/FGF12 Protein (Active)
| Code | Size | Price |
|---|
| PKSH032433-10ug | 10ug | £155.00 |
Quantity:
| PKSH032433-50ug | 50ug | £287.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Further Information
Abbreviation:
FGF-12;FGF12
Accession:
P61328-2
Activity:
Immobilized Human FGF-12 at 2ug/ml(100 ul/well) can bind Human FGFR3-Fc(Cat: PKSH033678). The ED50 of Human FGF-12 is 1. 27 ug/ml.
Background:
Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
Calculated MW:
20.5 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
19 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Thr181
Target Synonym:
Fibroblast Growth Factor 12;FGF-12;Fibroblast Growth Factor Homologous Factor 1;FHF-1;Myocyte-Activating Factor;FGF12;FGF12B;FHF1
UNIProt ID:
P61328