Recombinant Human Cornulin/CRNN Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH032281-10ug | 10ug | £460.00 |
Quantity:
| PKSH032281-50ug | 50ug | £658.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
The product is shipped on dry ice/polar packs. Upon receipt store it immediately at the storage temperature listed.
Storage:
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Further Information
Abbreviation:
Cornulin;CRNN
Accession:
Q9UBG3
Background:
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When Cornulin is overexpressed in oral squamous carcinoma cell lines, it regulates negatively cell proliferation by the induction of G1 arrest.
Calculated MW:
17.5 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-6His
ObservedMW:
15 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Ser140
Target Synonym:
Cornulin;53 kDa Putative Calcium-Binding Protein;53 kDa Squamous Epithelial-Induced Stress Protein;58 kDa Heat Shock Protein;Squamous Epithelial Heat Shock Protein 53;Tumor-Related Protein;CRNN;C1orf10;DRC1;PDRC1;SEP53
UNIProt ID:
Q9UBG3