Recombinant Human CD55/DAF Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH032222-10ug | 10ug | £435.00 |
Quantity:
| PKSH032222-50ug | 50ug | £567.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
The product is shipped on dry ice/blue ice. Upon receipt store it immediately at the storage temperature listed.
Storage:
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Further Information
Abbreviation:
CD55;DAF
Accession:
P08174
Background:
CD55 is a member of the RCA (regulators of complement activation) family. RCA proteins is characterized by the presence of four to 30 SCRs (short consensus repeats also called CCPs for control protein modules) in their plasmaexposed regions. CD55 containing four SCR modules is involved in the regulation of the complement cascade. CD55 is known to bind CD97 via the first SCR. It also binds physiologically generated C3 convertases with its second and third SCRs. Binding results in an accelerated ?decay?, or dissociation of active C3 convertases, thus blocking the development of C? attack complexes on nonforeign cells. It is known that viruses and bacteria also utilize multiple SCR sites for infection.
Calculated MW:
36.0 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
59 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Asp35-Ser353
Target Synonym:
Complement Decay-Accelerating factor;CD55;CR;CROM;DAF;TC
UNIProt ID:
P08174