Recombinant Human CD155/PVR Protein (His Tag)(Active)
| Code | Size | Price |
|---|
| PKSH031868-100ug | 100ug | £945.00 |
Quantity:
| PKSH031868-1mg | 1mg | £5,075.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
The product is shipped on dry ice/blue ice. Upon receipt store it immediately at the storage temperature listed.
Storage:
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Further Information
Abbreviation:
CD155;PVR
Accession:
NP_006496.3
Activity:
Immobilized human CD155 at 2 ug/ml (100 ul/well) can bind human DNAM1 with a linear ranger of 1. 28-32 ng/ml.
Background:
CD155; commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5); is a type I transmembrane single-span glycoprotein; and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV); an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension; migration and NK-cell killing; and thus efficiently prime cell-mediated tumor-specific immunity.
Calculated MW:
36.5 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
60-65 kDa
Purity:
> 97 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Asn 343
Target Synonym:
CD155;HVED;Necl-5;NECL5;PVS;TAGE4