Recombinant Human ACE2 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH032068-10ug | 10ug | £536.00 |
Quantity:
| PKSH032068-50ug | 50ug | £833.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
The product is shipped on dry ice/blue ice. Upon receipt store it immediately at the storage temperature listed.
Storage:
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Further Information
Abbreviation:
ACE2
Accession:
Q9BYF1
Background:
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don?t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Calculated MW:
84.6 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 300mM NaCl, 1mM ZnCl2, 10% Glycerol, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
103 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gln18-Ser740
Target Synonym:
Angiotensin-Converting Enzyme 2;ACE-Related Carboxypeptidase;Angiotensin-Converting Enzyme Homolog;ACEH;Metalloprotease MPROT15;ACE2
UNIProt ID:
Q9BYF1
References
- https://www.mdpi.com/1844936