Recombinant Human AKR1C3 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH032055-10ug | 10ug | £500.00 |
Quantity:
| PKSH032055-50ug | 50ug | £777.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
The product is shipped on dry ice/blue ice. Upon receipt store it immediately at the storage temperature listed.
Storage:
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Further Information
Abbreviation:
AKR1C3
Accession:
P42330
Background:
AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites.
Calculated MW:
37.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
38 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Tyr323
Target Synonym:
Aldo-Keto Reductase Family 1 Member C3;17-Beta-Hydroxysteroid Dehydrogenase Type 5;17-Beta-HSD 5;3-Alpha-HSD Type II Brain;3-Alpha-Hydroxysteroid Dehydrogenase Type 2;3-Alpha-HSD Type 2;Chlordecone Reductase Homolog HAKRb;Dihydrodiol Dehydrogenase 3;DD-3;DD3;Dihydrodiol Dehydrogenase Type I;HA1753;Indanol Dehydrogenase;Prostaglandin F Synthase;Testosterone 17-Beta-Dehydrogenase 5;Trans-1;2-Dihydrobenzene-1;2-Diol Dehydrogenase;AKR1C3;DDH1;HSD17B5;KIAA0119;PGFS
UNIProt ID:
P42330