SNCA Polyclonal Antibody
Code | Size | Price |
---|
E-AB-36111-20uL | 20uL | £125.00 |
Quantity:
E-AB-36111-60uL | 60uL | £172.00 |
Quantity:
E-AB-36111-120uL | 120uL | £237.00 |
Quantity:
E-AB-36111-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
Synuclein-α
Background:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Buffer:
PBS with 0.02% sodium azide,0.5% protective protein and 50% glycerol pH 7.4.
Calculated MW:
14kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300 ELISA 1:10000
Immunogen:
Synthesized peptide derived from the Internal region of human Synuclein-α.
ObservedMW:
15kDa
Purification method:
Affinity purification
Target Synonym:
Alpha synuclein;Alpha-synuclein;Alpha-synuclein;isoform NACP140;alphaSYN;MGC105443;MGC110988;MGC127560;MGC64356;NACP;Non A beta component of AD amyloid;Non A4 component of amyloid;Non A4 component of amyloid precursor;Non-A beta component of AD amyloid;Non-A-beta component of alzheimers disease amyloid;precursor of;Non-A4 component of amyloid precursor;Non-A4 component of amyloid;precursor of;OTTHUMP00000218549;OTTHUMP00000218551;OTTHUMP00000218552;OTTHUMP00000218553;OTTHUMP00000218554;PARK 1;PARK 4;PARK1;PARK4;Parkinson disease (autosomal dominant;Lewy body) 4;Parkinson disease familial 1;SNCA;Snca synuclein;alpha (non A4 component of amyloid precursor);SYN;Synuclein alpha;Synuclein alpha 140;Synuclein;alpha (non A4 component of amyloid precursor);SYUA
UNIProt ID:
P37840
References
- https://link.springer.com/article/10.1007/s12640-023-00637-4
- https://www.sciencedirect.com/science/article/pii/S0006899322001822