α-SMA Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-34268-20uL | 20uL | £125.00 |
Quantity:
| E-AB-34268-60uL | 60uL | £172.00 |
Quantity:
| E-AB-34268-120uL | 120uL | £237.00 |
Quantity:
| E-AB-34268-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
α-SMA
Background:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 (Actin, Alpha 2, Smooth Muscle, Aorta) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Moyamoya Disease 5. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include protein kinase binding. An important paralog of this gene is ACTG2. ACTA1 (Actin, Alpha 1, Skeletal Muscle) is a Protein Coding gene. Diseases associated with ACTA1 include Nemaline Myopathy 3, Autosomal Dominant Or Recessive and Myopathy, Congenital, With Fiber-Type Disproportion. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include structural constituent of cytoskeleton and myosin binding. An important paralog of this gene is ACTC1. ACTG2 (Actin, Gamma 2, Smooth Muscle, Enteric) is a Protein Coding gene. Diseases associated with ACTG2 include Visceral Myopathy and Chronic Intestinal Pseudoobstruction. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. An important paralog of this gene is ACTA2.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
42kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-2000, IHC 1:50-300, IF 1:50-1:200, ELISA 1:10000-20000
Immunogen:
Synthesized peptide derived from α-SMA
ObservedMW:
42kDa
Purification method:
Affinity purification
Target Synonym:
a actin;AAT6;ACTA;ACTA2;Actin alpha 2 smooth muscle aorta;Actin aortic smooth muscle;Actin;aortic smooth muscle;ACTSA;ACTVS;Alpha 2 actin;Alpha actin 2;Alpha cardiac actin;alpha sma;Alpha-actin-2;Cell growth inhibiting gene 46 protein;Cell growth-inhibiting gene 46 protein;GIG46;Growth inhibiting gene 46;MYMY5;ACTC;ACTC;ACTC1;Actin alpha cardiac muscle 1;Actin;alpha cardiac muscle 1;Alpha-cardiac actin;ASD5;CMD1R;CMH11;LVNC4;a actin;Actin alpha skeletal muscle;Actin;actin;alpha 1;skeletal muscle 1;actin;alpha 1;skeletal muscle;Actin;alpha skeletal muscle;actina;actine;ACTS;aktin;Alpha Actin 1;;ASMA;CFTD;CFTD1;CFTDM;MPFD;NEM1;NEM2;NEM3;nemaline myopathy type 3
UNIProt ID:
P62736,P68133,P63267
References
- https://www.nature.com/articles/s41467-022-30464-8
- https://www.sciencedirect.com/science/article/pii/S0141813022026228
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068511/
- https://www.sciencedirect.com/science/article/pii/S002432052200577X
- https://www.sciencedirect.com/science/article/pii/S0024320522009560
- https://www.mdpi.com/2150366
- https://www.mdpi.com/2073-4409/8/11/1435
- https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.5081
- https://www.mdpi.com/1587758
- https://www.sciencedirect.com/science/article/pii/S0022030223000644
- https://www.tandfonline.com/doi/abs/10.1080/21655979.2021.1954580
- https://jpet.aspetjournals.org/content/364/3/399.abstract