NBR1 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22148-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22148-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22148-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22148-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:4C6
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
NBR1
Background:
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.NBR1 (NBR1, Autophagy Cargo Receptor) is a Protein Coding gene. Diseases associated with NBR1 include Inclusion Body Myositis and Synucleinopathy. Among its related pathways are Mitophagy - animal. GO annotations related to this gene include ubiquitin binding and mitogen-activated protein kinase binding.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-300, IF 1:50-1:200
Immunogen:
Recombinant Protein of NBR1
Purification method:
Protein A purification
Target Synonym:
1A1 3B;1A13B;B box protein;Cell migration-inducing gene 19 protein;KIAA0049;M17S2;Membrane component chromosome 17 surface marker 2;Membrane component;chromosome 17;surface marker 2 (ovarian carcinoma antigen CA125);MIG 19;MIG19;Migration inducing protein 19;NBR 1;Nbr1;NBR1;autophagy cargo receptor;NBR1;Neighbor of BRCA1 gene 1;Neighbor of BRCA1 gene 1 protein;Next to BRCA1 gene 1 protein;Ovarian carcinoma antigen CA125;Protein 1A1-3B
UNIProt ID:
Q14596