CBX5 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22146-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22146-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22146-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22146-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:7B6
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CBX5
Background:
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-2000, IHC 1:50-300
Immunogen:
Recombinant Protein of HP-1α
ObservedMW:
22kDa
Purification method:
Protein A purification
Target Synonym:
Antigen p25;CBX5;CBX5;CG8409;Chromobox 5;Chromobox homolog 5 (HP1 alpha homolog;Drosophila);Chromobox homolog 5;Chromobox protein homolog 5;Epididymis luminal protein 25;HEL25;Heterochromatin protein 1 alpha;Heterochromatin protein 1;Heterochromatin protein 1 homolog alpha;HP1 alpha;HP1 alpha homolog;HP1;HP1A;HP1Hs alpha;Su(var)205
UNIProt ID:
P45973