Tau Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22141-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22141-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22141-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22141-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:8A3
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Tau Mouse (10E3)
Background:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-2000, IHC 1:100-200
Immunogen:
Synthetic Peptide of Tau
ObservedMW:
79kDa
Purification method:
Protein A purification
Target Synonym:
AI413597;AW045860;DDPAC;FLJ31424;FTDP 17;G protein beta1/gamma2 subunit interacting factor 1;MAPT;MAPTL;MGC134287;MGC138549;MGC156663;Microtubule associated protein tau;Microtubule associated protein tau isoform 4;Microtubule-associated protein tau;MSTD;Mtapt;MTBT1;MTBT2;Neurofibrillary tangle protein;Paired helical filament tau;Paired helical filament-tau;PHF tau;PHF-tau;PPND;PPP1R103;Protein phosphatase 1;regulatory subunit 103;pTau;RNPTAU;TAU;TAU;Tauopathy and respiratory failure;included
UNIProt ID:
P10636