BAX Monoclonal Antibody

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Elabscience
Product Code: E-AB-22128
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-22128-20uL20uL£125.00
Quantity:
E-AB-22128-60uL60uL£172.00
Quantity:
E-AB-22128-120uL120uL£237.00
Quantity:
E-AB-22128-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:1D8
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western Blot analysis of 1) Hela, 2) C2C12, 3) PC-12 cells using Bax Monoclonal Antibody at dilution of 1:1000.
2 / 2
Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using Bax Monoclonal Antibody at dilution of 1:200.
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Western Blot analysis of 1) Hela, 2) C2C12, 3) PC-12 cells using Bax Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using Bax Monoclonal Antibody at dilution of 1:200.

Documents

Further Information

Abbreviation:
BAX
Background:
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-2000, IHC 1:100-200
Immunogen:
Synthetic Peptide of Bax
ObservedMW:
20kDa
Purification method:
Protein A purification
Target Synonym:
Apoptosis regulator BAX;BAX;Bax-protein;BAX;BAXA;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;Bcl-2-like protein 4;BCL2 associated X protein;BCL2 associated X protein omega;BCL2 associated X protein transcript variant delta2;Bcl2-L-4;BCL2L4;membrane isoform alpha
UNIProt ID:
Q07812

References

  • https://www.sciencedirect.com/science/article/pii/S0168822722008804
  • https://link.springer.com/article/10.1007/s11356-023-25636-y
  • https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-019-2768-1