MICU1 Monoclonal Antibody

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Elabscience
Product Code: E-AB-22114
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-22114-20uL20uL£125.00
Quantity:
E-AB-22114-60uL60uL£172.00
Quantity:
E-AB-22114-120uL120uL£237.00
Quantity:
E-AB-22114-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:4E7
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western Blot analysis of 1) MCF7, 2) Mouse brain, 3) Rat brain with MICU1 Monoclonal Antibody.
2 / 2
Immunohistochemistry of paraffin-embedded Mouse testis tissue using MICU1 Monoclonal Antibody at dilution of 1:200.
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Western Blot analysis of 1) MCF7, 2) Mouse brain, 3) Rat brain with MICU1 Monoclonal Antibody.
Immunohistochemistry of paraffin-embedded Mouse testis tissue using MICU1 Monoclonal Antibody at dilution of 1:200.

Documents

Further Information

Abbreviation:
MICU1
Background:
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:200, IF 1:100-1:300
Immunogen:
Recombinant Protein
ObservedMW:
55kDa
Purification method:
Protein A purification
Target Synonym:
Allergen Hom s 4;ara CALC;atopy related autoantigen;atopy related autoantigen CALC;Atopy-related autoantigen CALC;CALC;calcium binding atopy related autoantigen 1;Calcium uptake protein 1;calcium uptake protein 1;mitochondrial;Calcium-binding atopy-related autoantigen 1;CBARA1;EFHA3;FLJ12684;MICU1;MICU1;mitochondrial;mitochondrial calcium uptake 1;MPXPS
UNIProt ID:
Q9BPX6