JNK2 Polyclonal Antibody

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Elabscience
Product Code: E-AB-15735
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-15735-20uL20uL£125.00
Quantity:
E-AB-15735-60uL60uL£172.00
Quantity:
E-AB-15735-120uL120uL£237.00
Quantity:
E-AB-15735-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human esophagus cancer using JNK2 Polyclonal Antibody at dilution of 1:30
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Immunohistochemistry of paraffin-embedded Human lung cancer using JNK2 Polyclonal Antibody at dilution of 1:30
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Immunohistochemistry of paraffin-embedded Human esophagus cancer using JNK2 Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human lung cancer using JNK2 Polyclonal Antibody at dilution of 1:30

Documents

Further Information

Abbreviation:
JNK2
Background:
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
48kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human MAPK9
ObservedMW:
Refer to figures
Purification method:
Affinity purification
Target Synonym:
c Jun kinase 2;C Jun N terminal kinase 2;c-Jun N-terminal kinase 2;JNK 55;JNK-55;JNK2 alpha;JNK2;JNK2 beta;JNK2A;JNK2alpha;JNK2B;JNK2BETA;Jun kinase;MAP kinase 9;MAPK 9;Mapk9;Mitogen activated protein kinase 9;Mitogen-activated protein kinase 9;MK09;P54a;p54aSAPK;PRKM9;Protein kinase;mitogen-activated;9;SAPK alpha;SAPK;SAPK1a;Stress activated protein kinase 1a;Stress-activated protein kinase JNK2
UNIProt ID:
P45984