CYP1A1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-14029
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-14029-20uL20uL£125.00
Quantity:
E-AB-14029-60uL60uL£172.00
Quantity:
E-AB-14029-120uL120uL£237.00
Quantity:
E-AB-14029-200uL200uL£344.00
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Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western Blot analysis of Mouse liver tissue using CYP1A1 Polyclonal Antibody at dilution of 1:400
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Western Blot analysis of Mouse liver tissue using CYP1A1 Polyclonal Antibody at dilution of 1:400

Documents

Further Information

Abbreviation:
CYP1A1
Background:
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
58kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein of human CYP1A1
ObservedMW:
Refer to figures
Purification method:
Affinity purification
Target Synonym:
AHH;AHRR;Aryl hydrocarbon hydroxylase;CP11;CP1A1;CYP 1;CYP1;cyp1a1;CYPIA1;Cytochrome P1 450 dioxin inducible;Cytochrome P1-450;Cytochrome P450 1A1;Cytochrome P450 family 1 subfamily A polypeptide 1;Cytochrome P450 form 6;Cytochrome P450 subfamily I (aromatic compound inducible) polypeptide 1;Cytochrome P450-C;Cytochrome P450-P1;Flavoprotein-linked monooxygenase;Microsomal monooxygenase;P1 450;P450 C;P450 form 6;P450 P1;P450DX;Xenobiotic monooxygenase
UNIProt ID:
P04798

References

  • https://www.atsjournals.org/doi/pdf/10.1164/rccm.202009-3385LE
  • https://www.mdpi.com/2076-3921/10/9/1484