AMPK alpha1 Monoclonal Antibody

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Elabscience
Product Code: E-AB-22248
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-22248-20uL20uL£125.00
Quantity:
E-AB-22248-60uL60uL£172.00
Quantity:
E-AB-22248-120uL120uL£237.00
Quantity:
E-AB-22248-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:9G3
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human lung carcinoma tissue using AMPK alpha1 Monoclonal Antibody at dilution of 1:200.
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Immunohistochemistry of paraffin-embedded Human lung carcinoma tissue using AMPK alpha1 Monoclonal Antibody at dilution of 1:200.

Documents

Further Information

Abbreviation:
AMPK alpha1
Background:
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-2000, IHC 1:100-200
Immunogen:
Recombinant Protein of AMPKα1 of PRKAA1
ObservedMW:
62kDa
Purification method:
Protein A purification
Target Synonym:
5 AMP activated protein kinase alpha 1catalytic subunit;5 AMP activated protein kinase catalytic alpha 1 chain;5' AMP activated protein kinase catalytic subunit alpha 1;5'-AMP-activated protein kinase catalytic subunit alpha-1;AAPK1;AAPK1;ACACA kinase;acetyl CoA carboxylase kinase;AI194361;AI450832;AL024255;AMP -activate kinase alpha 1 subunit;AMP-activated protein kinase;catalytic;alpha -1;AMPK 1;AMPK alpha 1;AMPK alpha 1 chain;AMPK;AMPK subunit alpha-1;AMPK1;AMPKa1;AMPKalpha1;C130083N04Rik;cb116;EC 2.7.11.1;HMG CoA reductase kinase;HMGCR kinase;hormone sensitive lipase kinase;Hydroxymethylglutaryl CoA reductase kinase;im:7154392;kinase AMPK alpha1;MGC33776;MGC57364;OTTHUMP00000161795;OTTHUMP00000161796;PRKAA 1;PRKAA1;Protein kinase AMP activated alpha 1 catalytic subunit;SNF1-like protein AMPK;SNF1A;Tau protein kinase PRKAA1;wu:fa94c10
UNIProt ID:
Q13131