VE-Cadherin Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22244-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22244-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22244-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22244-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:8E5
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
VE-Cadherin
Background:
This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-200
Immunogen:
Synthetic Peptide of VE-Cadherin
Purification method:
Protein A purification
Target Synonym:
7B 4;7B4;7B4 antigen;CADH5;Cadherin 5;Cadherin 5 type 2;Cadherin 5;type 2 (vascular endothelium);Cadherin 5;type 2;VE cadherin (vascular epithelium);cadherin;vascular endothelial;cadherin;vascular endothelial;1;Cadherin-5;Cadherin5;CD 144;CD144;CD144 antigen;CDH 5;CDH5;CDH5 protein;Endothelial specific cadherin;FLJ17376;OTTHUMP00000174777;Vascular endothelial cadherin;Vascular epithelium cadherin;VE Cad;VE-cadherin;VEC
UNIProt ID:
P33151