CHOP Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22243-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22243-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22243-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22243-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:1E1
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CHOP Mouse (1E1)
Background:
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-200
Immunogen:
Synthetic Peptide of CHOP
Purification method:
Protein A purification
Target Synonym:
C/EBP homologous protein;C/EBP Homology Protein;C/EBP zeta;C/EBP-homologous protein 10;C/EBP-homologous protein;CCAAT/enhancer binding protein homologous protein;CEBPZ;CHOP 10;CHOP;CHOP-10;CHOP10;DDIT 3;DDIT-3;Ddit3;DDIT3;DNA Damage Inducible Transcript 3;DNA damage-inducible transcript 3 protein;GADD 153;GADD153;Growth Arrest and DNA Damage Inducible Protein 153;Growth arrest and DNA damage inducible protein GADD153;Growth arrest and DNA damage-inducible protein GADD153;MGC4154
UNIProt ID:
P35638