BECN1 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22238-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22238-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22238-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22238-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:5A11
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
BECN1
Background:
Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-200
Immunogen:
Synthetic Peptide of Beclin-1
Purification method:
Protein A purification
Target Synonym:
APG6;ATG 6;ATG6;ATG6 autophagy related 6 homolog;Bcl-2-interacting protein beclin;Beclin 1 (coiled coil moesin like BCL2 interacting protein);Beclin 1 autophagy related;Beclin-1;Beclin1;BECN 1;Becn1;BECN1;Coiled coil myosin like BCL2 interacting protein;Coiled-coil myosin-like BCL2-interacting protein;GT197;Protein GT197;VPS 30;VPS30
UNIProt ID:
Q14457