BAX Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22212-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22212-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22212-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22212-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:1C1
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
BAX
Background:
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-200
Immunogen:
Synthetic Peptide of Bax
Purification method:
Protein A purification
Target Synonym:
Apoptosis regulator BAX;BAX;Bax-protein;BAX;BAXA;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;Bcl-2-like protein 4;BCL2 associated X protein;BCL2 associated X protein omega;BCL2 associated X protein transcript variant delta2;Bcl2-L-4;BCL2L4;membrane isoform alpha
UNIProt ID:
Q07812