c-Fos Monoclonal Antibody

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Elabscience
Product Code: E-AB-22158
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-22158-20uL20uL£125.00
Quantity:
E-AB-22158-60uL60uL£172.00
Quantity:
E-AB-22158-120uL120uL£237.00
Quantity:
E-AB-22158-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: 6A3
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western Blot analysis of 1) Hela, 2) 293T, 3) Mouse brain, 4) Rat brain using c-Fos Monoclonal Antibody at dilution of 1:2000.
2 / 2
Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using c-Fos Monoclonal Antibody at dilution of 1:200.
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Western Blot analysis of 1) Hela, 2) 293T, 3) Mouse brain, 4) Rat brain using c-Fos Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using c-Fos Monoclonal Antibody at dilution of 1:200.

Documents

Further Information

Abbreviation:
c-Fos
Background:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300 ELISA 1:40000
Immunogen:
Recombinant Protein
ObservedMW:
62kDa
Purification method:
Protein A purification
Target Synonym:
Activator protein 1;AP 1;C FOS;Cellular oncogene c fos;Cellular oncogene fos;FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS);FBJ murine osteosarcoma viral oncogene homolog;FBJ murine osteosarcoma viral v fos oncogene homolog;FBJ Osteosarcoma Virus;FOS;FOS protein;FOS;G0 G1 switch regulatory protein 7;G0/G1 switch regulatory protein 7;G0S7;Oncogene FOS;p55;proto oncogene c Fos;Proto oncogene protein c fos;Proto-oncogene c-Fos;v fos FBJ murine osteosarcoma viral oncogene homolog
UNIProt ID:
P01100